Southern Illinois Vacation Packages 2026 from $573

Southern Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Hampton Inn By Hilton St Louis Airport

Woodson Terrace

$573

per person

Apr 10 - Apr 15

found 1 day ago

Roundtrip flight included

Dallas (DFW) to St. Louis (STL)

Self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate freebies like continental breakfast, WiFi in public areas, and a roundtrip airport shuttle. Express check-in and express check-out are also provided.

The Wildwood Hotel

$797

per person

May 21 - May 26

just found

Roundtrip flight included

San Francisco (SFO) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

$667

per person

May 15 - May 18

found 1 day ago

Roundtrip non-stop flight included

San Francisco (SFO) to St. Louis (STL)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.

The Knight Center at Washington University

$746

per person

May 21 - May 26

just found

Roundtrip flight included

San Francisco (SFO) to St. Louis (STL)

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

DoubleTree by Hilton St. Louis Forest Park

Central West End

$604

per person

May 15 - May 18

found 1 day ago

Roundtrip non-stop flight included

San Francisco (SFO) to St. Louis (STL)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, a grocery/convenience store, and a lobby fireplace are also offered.

Top Southern Illinois hotels deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

$94 nightly

$106 total

Mar 17 - Mar 18

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Best Western Delta Inn

1509 Hampton Dr Effingham IL

Free Cancellation

Reserve now, pay when you stay

$85 nightly

$95 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$106 nightly

$123 total

Apr 5 - Apr 6

Total with taxes and fees

Pool

Hot Tub

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$111 nightly

$125 total

Apr 3 - Apr 4

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Comfort Suites Mount Vernon

404 South 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$110 nightly

$124 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$51 nightly

$59 total

Mar 12 - Mar 13

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

A summer sunset over Garden of the Gods in Southern Illinois; Shutterstock ID 356954318; Purchase Order: -

Garden of the Gods Recreation Area

5/5(6 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

Superman Statue

4.5/5(104 reviews)

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Frequently asked questions

How much are vacation packages to Southern Illinois?

Your travel fantasies can become a reality in Southern Illinois for as little as $573. Our package deals include flights and hotels, so booking your trip will be a piece of cake. The only thing you'll need to worry about is what amazing attraction you'll head to first.

Where can I get the best vacation package deals for Southern Illinois?

With at least 400 air carriers and 1,000,000 properties around the world, it's tough to beat Travelocity. Take advantage of our comprehensive range and grab an affordable Southern Illinois vacation package. Doesn't it feel amazing when travel is that easy?

Why should I purchase my Southern Illinois vacation package via Travelocity?

The three S's — savings, support and a stress-free booking — are just the beginning. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.

Can I save on my Southern Illinois car rental if I bundle it with a hotel or flight?

You can with our Southern Illinois vacation packages. With one of these, there are lots of ways to stretch your budget further. Combine any two or more car, flight, hotel and tour bookings and watch the savings start to pile up. With your own set of wheels, all the landmarks around Southern Illinois are just a road trip away.

Which airport is best for Southern Illinois?

Williamson County Regional Airport (MWA) is the main airport that offers flights in and out of Southern Illinois.

What is there to do in Southern Illinois?

Southern Illinois boasts hidden gems at every turn, however make sure you see Shawnee National Forest and Southern Illinois University while you're in town. These two attractions are popular with visitors.